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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27e4b27a45c1f2060d1dcb01697b16c44ca4228004421d3365f16a6c01967cc' 
  AND token = 'CXwDKKT8XlVzb84vR3z3soSu5AFJEn5X4DKldBz4CEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}