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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '544438c35899ec70e2f9d011c520af90382c809ff54cb7b99ced1a4e7f870454' 
  AND token = 'L5V5cd8Blm8c/LcrIfzFwyZwXL6gyOT9n28bWgIAiEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}