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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187022476d6b65cbd4f5a567b14ecb2f104fcd7f66734cf9e7be8df2527cf2f1' 
  AND token = 'G1ZLj3jHiqObaEQXzfISN4usAfE8/a5UyHkd0ja6UKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}