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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b939185819fe2d89d6b7b79dc2fdb52a423f8f12b60e3193f58c2628c9f0665' 
  AND token = 'FVWkG7Zo6docr4S2qftvwjGbr48IBhcXhyskQxQHIdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}