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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd19b181f5b74a72bbc20d6ff2653ba7fc0474c337a7fa1d16545def8c02c72' 
  AND token = 'I35DLaHq/13637LCCoytaED4ZU/M3UtE26cshnhMl+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}