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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9388c5a55c4998e88472a0f9db3cb20fca92a845e6edcf67bd01a8e3b856c1c6' 
  AND token = 'qRYszk/I3PvhcgNVky5HrVk985cwFAxXnU9KSyB/kqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}