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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b6395cb7469e89fb20d6ab017e6d9fad83ac8fd268a0c7a36738e57b00672c' 
  AND token = '3xppQ6EAVHdsLf1/1+9D54cuTZqfQlm4EsuLDd0Wx8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}