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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354d266be4dd0ae7d548eaea7812540d59f81c042a5c9b53be9331ef86b6a784' 
  AND token = 'EAhwF/hcHxaxB6pHEoLq1CzDjwm3y6z4XwnUJy5KaEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}