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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e621a00caa46e54e1b5baae2e116decb6eadb0d6f80b6d5db4e867fdb8ee261' 
  AND token = 'Ia51fgnyICfGDQj6mDfS/nh+J5nKp6t2vAGIzoOgXA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}