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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd7b4619018465e59e25f99b182b908dfd926328eb8c1f73eb27cf2c082462b1' 
  AND token = 'WM7UHBnxLlXN97oA5B1rQpGYOg7ibOaH0cptrNu2XxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}