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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749ea97e3bc9e481604182180f43f832a287a85a2e2a996bf4c9f4c87a533d4d' 
  AND token = 'WQdc5E8hrzb+wlXLU3lE10xww0CutrQ8XdhMug+pEK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}