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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49113e55220658fc4f99a7634f151878e1265fa83fe4c943a0c40ff084b01a82' 
  AND token = '736/yD00Z8ZdJTlTbWv7KFFXrwzTHVECuq7bfLwkCs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}