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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39396d9c4a1bcff614bea01d1f3cc865ccc753bf4edcfdceec0e67eebe766a4f' 
  AND token = '9f6O5OP3dima4S/OWan/SDYXa1+O85a2BQoQRvQAIog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}