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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e28167a45acf227cb9492ac051c36bb8ab508a37d9be7bf76b16933b624176' 
  AND token = 'si4GMtQH97psgoTsg7y6biwWRewMbJ7PxDhwCoXKIPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}