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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c451cd31d730ec1d162bbac5d580ec8dccc1fa5f9f08d01ab2802c336cd7e528' 
  AND token = 'cvWYP+Qv0wg+E5Quw5B9+0kW/qYAcpBCLoIOEe6Kufg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}