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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffa4645e02e7c65da060abc13de2f3fc22f7c9ad5b230c7b4fbc22566df2f946' 
  AND token = 'yZt+3n1/MzbF5GEma/FaD5j+/W9zzDGkswdi6AkBF4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}