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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41d0b446392c876d41890f3290ac9840d0d05fd7ee07b4c48d9fa1204723676' 
  AND token = 'JMFPLDRzpviBA1ZQeDFsxJ/BEkuSwxBst4QQP3YKes8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}