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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '974f4eee38064cbd9b867352ea6910738dc1190ee7217e98d7c274b90f1015b6' 
  AND token = '9B4Es2HH/bvaAaR4ykTq8Hd4OYmXYjdFbxznsTEHFu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}