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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '520601c35cd3b5bbc9911bc4f8b65b9112e2eb33bf0eeb8670b4c0d9af850d82' 
  AND token = 'dZ4r/MuUfLGSEYSUhvyl2yh5OaB/2XSXzmq0kolT97o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}