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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b426b020012230f6929b80ea8239ad94f10b3bc0aa3178de5a86d234d2ee2973' 
  AND token = 'f/v6yfCl0RXer1QdrtrV5Fxt+MPQ+1L8akyT4ofM1Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}