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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42aeec96f75c50a0467b2a8448f05b3a72d217f32ea15564124c2afd86ccc73e' 
  AND token = 'JzIyVygEhWRvwY1JxRHKTl8Y3+UIMyP5wt6Ak8w1dtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}