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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c93eb47566fe43a7c1c44d9ffd003b85f272f9b648ddc1ace4cfbc4544933d' 
  AND token = 'ki7XI1WA2TEXLmKcuVpWnGMtkKSV4mlsz6rdiI0KvWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}