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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29353addb1b77859002eb1a05a20777d58eba80ff1aef0b16922078c8e708bfa' 
  AND token = 'PNO+zqhIYcH+Z01HTULqKQQkJc7zcKfZ5tMsAjnjbe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}