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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def0424f13916378396653735040ba7bf872a50ed885899abdfaae79c030272b' 
  AND token = '1dFA+eSU1Obp3CEdU6sSHgg3cXLCeATmpZcxzEkFgwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}