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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c768ed9aa5acf1280d95c4d5d17b230feb6c777509baf0395f7f779861bf059' 
  AND token = 'ZSTsmLvXTA4Khp09UGwikiuJbKKpzs5X6WTbveQK7Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}