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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb45a327d1889317b619a91b2100831089cc8d25be41ec08564a953c38683d05' 
  AND token = 'VXfa6g2MC6YSurYgZ6s3yAMgeGkgBdvzMx1ZDQKk2zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}