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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f4e291e34f715339a3712987970d26dfdcbea8b393da054ee978e4e5b0165e' 
  AND token = 't85cqBc8hO/upjoB/+ho8PDWz082mx2NqAqVfhn3I9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}