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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b72216b17744d9758b6fc1a53e65546dc590e26274ebbc865abdd53e6311b0' 
  AND token = 'a1FQ5zqSkZYcWY6mzgQT9OguyVx8IeimS0ql60aFRpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}