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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a0f3ced018e923b0905e4e0a3215defeff3adcd46aa78a99c241fdab6dda37' 
  AND token = 't7Vpul1YqCk2nlGa0pKChJ8GQpjvZyMCnxsFRFOX7YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}