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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7e6954b186c764f3768e20f34848730a6fec997c9cc71055b7a928d7ef34e65' 
  AND token = 'QuPZz/FJIPInmrFL78H0WRU7YZBNtob0HGiCA0g0XpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}