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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e656d215ce71da926bb57ef67f29ac466fc52daa4315b957121e6d6d66f77f8' 
  AND token = 'quLyP/MxlR9Hvt9yBU/qol/T6sgeOfBN4QVc+1xt8AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}