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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad5ab39ceeeb559aec04f100b6aec122018a47cd5ac88450217aab654e74110' 
  AND token = 'mVjnDECsEHbhMKmCqmg3LEH3xU2DVjid+1Sa6sN8wMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}