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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e866b1f98bec36b5388fb4a505c2b34d80eb076a0cb7776d788220d861d8c241' 
  AND token = 'eLVn54TVMQo9M45m25FijcSsWPMI+oyUi5DT8/8PfEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}