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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517eb26c636ef559166d043ae771945f4bdf98534c6c34319c762210e6fc973c' 
  AND token = '0x2NJH9h8q+7kzFPn4hsbd2eu4CSFbgoWIVmwtA4X38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}