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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4367ec36dc6bd41981833ff43a6f92bee968eacf55bbd3bb5af66d6f652afbbb' 
  AND token = '4jrwOEeH2/BNwiBlk7gZeVin53G84tzl5M29RtAODyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}