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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b50bcb4af4b59b230896bba4bc285f5fa01c2be67109c9c1f15ddca9f0f893' 
  AND token = 'C2vVHwL+ajYI1MkV/uMcH22csqInP/C+2IUcJi+0qYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}