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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19d2b8c1f8c006402c10d76527a68cfa72cdf45773fa9e45988999431a1ace01' 
  AND token = 'xKkG798o9QV8NmfNRae3+BqLG89llz/m4W+28r0UGQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}