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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1acbe2427433d3b1631f6c242304b4b3ebc5729d38eca1486d438673968e19d4' 
  AND token = 'N+kmLA/xxb0TEXjykqpTD2gOAthd3xcKLve4VwH/2Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}