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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e57587cd2e9e435a2f6bafe45baefabe506f5ff5c8044c65e82c37f5f372d7c' 
  AND token = 'iZuFYQYywGBNsLQnXNnEsXFjmxsLnnW36iXy2vwH46U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}