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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49153d2b4bd56b7197278e5a9a337ec0331b18418a6b2d23507f4d82a333b2bb' 
  AND token = 'Nja4KuzUBPbgJKlqk84aPyjzpMSFcCSrOgG3LJbMuNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}