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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387ce4dfe2a98e8c705e15ac6a1eb0dad01335267b017799ddc354450e769bd4' 
  AND token = '2CmlLd8/nzWsAjECMUfrs7jO3z64j6Erp5PkRGe+i4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}