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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b0b1fb1afdaefafcb2b19ed41afd9773426b49b801577a1159c83e5c99ed16' 
  AND token = 'Jk3PPuXCHcp0eGPcfI6+QbaDkoztAjYMj8yqrip7qhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}