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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d380f795c8624257edad47c86f56a27bee510bb2949df34279f9cd878460ca' 
  AND token = '2o7WW+eOdshnEWvoO84I9S9RwOX6SMPCbYynbROIEv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}