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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e46ef910997cd366c614e664c0c7cc0052b3aa34de73150234b044662b543a' 
  AND token = 'bTgTQZD/eiNAm067x2KoFufNkmgzhmcapEOVh/EgoBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}