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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61864d273bf48e720de176f62c11beea1f1fdcfd348c885640749f1f8bf0770b' 
  AND token = 'kihn3u+TsFU9Q5X1zFEH9hA6wwKd+ucsY9lo4mNTRjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}