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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f00f4e11f31715c5fc7fad910308ca5a5deea66cb221d4af4da1be41b455a72' 
  AND token = '753ynGJxVMFZvbainN/c3Mfnf31leaLBDAKVe39HC5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}