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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe23ceb3aed744518835f70db0365058464964f6d8e78bfc6bd5ae93e83f0e3' 
  AND token = 'f5eq5UkE6dH/axMvPNMsHu2oHnmF9KIdqmN+moWwtUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}