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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c079fc1bc43ef274a26481313e0e68e6ebb2edf24d69270c998d023eaaff41c' 
  AND token = 'v/aqV+qOWLoG4AHgvBXEy0xCEljvWEuZzAuNTI4ehB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}