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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646e533c599071259d3599b3fba18e2667625c47029a14d26dd341dac9547676' 
  AND token = 'z//d06myb+LM720ev8VD6XyKYUOEgHYHzk2UKQ+diKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}