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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d18b61beb0328335dc0b003fecdaf66bd9e893870b404c23434c7312007bd64' 
  AND token = 's5PVlfo9uT6d/hwAlYQquJmrohyTf/qPDB/XR2hnIqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}